Dietary fiber helps maintain gut health: Study

A team of researchers have discovered that by-products of the digestion of dietary fiber by gut microbes act as the right fuel to help maintain gut health.

Published: 13th August 2017 04:40 PM  |   Last Updated: 13th August 2017 04:40 PM   |  A+A-

By ANI

WASHINGTON D.C: A team of researchers have discovered that by-products of the digestion of dietary fiber by gut microbes act as the right fuel to help maintain gut health.

Researchers from University of California - Davis Health System identified the host receptor peroxisome proliferator receptor gamma (PPARg) as the regulator responsible for maintaining this cycle of protection.

They explained that when this host signaling pathway malfunctions, it leads to increased oxygen levels in the gut lumen and these higher oxygen levels make us more susceptible to aerobic enteric pathogens such as Salmonella or Escherichia coli, which use oxygen to edge out competing beneficial microbes.

Senior study author Andreas Bäumler from UC Davis Health said that the research suggests that one of the best approaches to maintaining gut health might be to feed the beneficial microbes in intestines dietary fiber.

"While it is known that the gut is the site of constant turf wars between microbes, our research suggests that signals generated by beneficial microbes drive the intestinal tract to limit resources that could lead to an expansion of potentially harmful microbes," he explained.

The study describes gut microbes as "partners" in the body's defense against potential infectious agents, such as Salmonella.

Resident gut microbes metabolise indigestible dietary fiber to produce short-chain fatty acids, which signal cells lining the large bowel to maximise oxygen consumption, thereby limiting the amount of oxygen diffusing into the gut lumen (the open space within the intestine that comes into direct contact with digested food.)

First study author Mariana X. Byndloss noted that the beneficial gut bacteria that are able to breakdown fiber do not survive in an environment rich in oxygen, which means that our microbiota and intestinal cells work together to promote a virtuous cycle that maintains gut health.

The research appears in journal Science.

Stay up to date on all the latest Health news with The New Indian Express App. Download now

Comments

Disclaimer : We respect your thoughts and views! But we need to be judicious while moderating your comments. All the comments will be moderated by the newindianexpress.com editorial. Abstain from posting comments that are obscene, defamatory or inflammatory, and do not indulge in personal attacks. Try to avoid outside hyperlinks inside the comment. Help us delete comments that do not follow these guidelines.

The views expressed in comments published on newindianexpress.com are those of the comment writers alone. They do not represent the views or opinions of newindianexpress.com or its staff, nor do they represent the views or opinions of The New Indian Express Group, or any entity of, or affiliated with, The New Indian Express Group. newindianexpress.com reserves the right to take any or all comments down at any time.

FIFA-World-Cup-2018