How gut bacteria may increase obesity risk

The gut flora in the intestines may cause health benefits for some people, whereas it increases the risk of obesity in the others.

Published: 25th February 2018 02:31 PM  |   Last Updated: 25th February 2018 03:01 PM   |  A+A-

Obesity in children is a rising concern.


LONDON: The presence of gut flora in the intestines may cause health benefits for some people, whereas it increases the risk of obesity in the others, researchers have claimed.

While sourcing a new link between gut bacteria and obesity, the animal based study found that certain amino acids in our blood can be connected to both obesity and the composition of the gut microbiome.

Obesity-related metabolites were linked to four different intestinal bacteria namely Blautia, Dorea and Ruminococcus in the Lachnospiraceae family, and SHA98, the researchers noted.

The study, published in the Journal of Clinical Endocrinology and Metabolism, mentioned that the gut microbiota affects our metabolism and lead to cardiovascular diseases and Type 2 diabetes.

Previous studies have shown that people with these diseases have varying occurrence of different metabolites, that is small molecules or metabolic residues, in the bloodstream. 

The researchers analysed blood plasma and stool samples from 674 participants in the Malmö Offspring Study (MOS).

They found 19 different metabolites that could be linked to the person's body mass index (BMI); glutamate and so-called BCAA (branched-chain and aromatic amino acids) had the strongest connection to obesity.

"The differences in BMI were largely explained by the differences in the levels of glutamate and BCAA. This indicates that the metabolites and gut bacteria interact, rather than being independent of each other," said Marju Orho-Melander, Professor at Lund University in Sweden.

Previous studies have also shown that the manipulation in the gut bacteria may cut down diabetes, bowel diseases and obesity risk.

Stay up to date on all the latest Health news with The New Indian Express App. Download now
(Get the news that matters from New Indian Express on WhatsApp. Click this link and hit 'Click to Subscribe'. Follow the instructions after that.)


Disclaimer : We respect your thoughts and views! But we need to be judicious while moderating your comments. All the comments will be moderated by the editorial. Abstain from posting comments that are obscene, defamatory or inflammatory, and do not indulge in personal attacks. Try to avoid outside hyperlinks inside the comment. Help us delete comments that do not follow these guidelines.

The views expressed in comments published on are those of the comment writers alone. They do not represent the views or opinions of or its staff, nor do they represent the views or opinions of The New Indian Express Group, or any entity of, or affiliated with, The New Indian Express Group. reserves the right to take any or all comments down at any time.

flipboard facebook twitter whatsapp