Implant to help restore facial movement after paralysis

While reconstructive surgery approaches such as nerve and muscle transfers can restore some facial movement, these techniques have important shortcomings.

Published: 07th January 2019 01:44 PM  |   Last Updated: 07th January 2019 01:44 PM   |  A+A-

Image used for representation.

By PTI

BOSTON: An implantable device may help restore natural facial movement in patients with one-sided facial paralysis, scientists say.

According to a study published in the journal Plastic and Reconstructive Surgery, experiments in animals show promising results with a "bionic face" approach to facial reanimation -- using electrical signals from the uninjured side of the face to trigger muscle movement on the paralysed side.

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Such an approach would represent a paradigm shift in the management of hemifacial palsy, according to Nate Jowett of Harvard Medical School in the US, who led the research.

Hemifacial palsy is a "devastating clinical condition" leading to functional, aesthetic, and communication problems.

While reconstructive surgery approaches such as nerve and muscle transfers can restore some facial movement, these techniques have important shortcomings.

For example, while patients may regain some ability to smile, it requires a conscious effort to do so.

The development and "proof of principle" of a new technique using functional electrical stimulation to restore motion of the face in hemifacial palsy.

To evoke more natural and appropriate movements, the stimulation of the paralysed side is linked to the electrical activity on the unaffected side to produce paired muscle contractions.

The researchers implanted tiny electrically-shielded cuff electrodes around the facial nerve of rats with experimentally induced hemifacial palsy.

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Electrical stimulation was delivered to produce eye blinks and whisker movements of varying durations and amplitudes.

Movements were evoked by linking stimulation of the paralysed side driven to movements on the uninjured side.

The "paired muscle contractions" produce more natural, normal-appearing movements.

The researchers note that most facial expressions, especially positive ones, are symmetrical.

Previous studies have reported the basic concept of using signals from the healthy side of the face to drive functional electrical stimulation of paralysed facial muscles.

The new research addressed some key technical challenges affect the long-term success of this approach -- including providing more natural, spontaneous smile and other facial movements while blocking unwanted, involuntary movements.

While the preliminary experiments in rats are encouraging, there's a long way to go before the "bionic face" can be refined enough for testing in human patients with hemifacial palsy, researchers said.

They plan further studies to develop a miniaturised, fully implantable neuroprosthetic device for hemifacial reanimation.

"Though the ultimate goal of reanimation is to restore dynamic motion of the entire facial musculature, restoration of three symmetric facial movements alone - brow elevation, blink, and smile - would dramatically improve outcomes," said Jowett.

Researchers believe that the combination of proximal neural blockade with distal functional electrical stimulation might also prove useful in the treatment of other peripheral nerve disorders, such as abnormal muscle contractions or nerve pain.

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