Scholar suggests new vaccine for TB

SHIMOGA: City based scholar Sriranjini’s research paper on ‘Design and Development of Potent Vaccine to Tuberculosis by Reverse Vaccinology Approach,’ which was published in the renowned Bio V

Published: 31st January 2012 05:07 AM  |   Last Updated: 16th May 2012 06:25 PM   |  A+A-

SHIMOGA: City based scholar Sriranjini’s research paper on ‘Design and Development of Potent Vaccine to Tuberculosis by Reverse Vaccinology Approach,’ which was published in the renowned Bio Vaccine Science

Journal, has become a milestone in the field of study on tuberculosis.  

Sriranjini, who is pursuing her graduation in BV Bhoomaraddi College of Engineering and Technology at Hubli, told reporters on Monday that people suffering from tuberculosis and her interest in science inspired her to do the research. Despite the advance in science, many people still suffer from tuberculosis and except BCG vaccine, no other effective vaccine has been developed to root out the disease, she added.

She explained that tuberculosis claims many number of people in the world annually, she said it was endemic in most of the countries but resurgent in developed and developing countries where the number of HIV infected people is more. The bacteria causing tuberculosis belongs to a diverse group of micro-organisms known as mycobacterium which are prevalent in human beings, he said.

She said, “My paper aims at developing a vaccine against tuberculosis by reversing the vaccinology approach. Mycobacterium Tuberculosis, the bacteria which causes the disease, will have more than 8,000 proteins. A protein which has less identity and e-value was selected after screening of all proteins. From this, antigen determinants were found, out of which HRRAPL antigenic determinant was found to be good vaccine candidate through docking analysis,” she explained.

Stay up to date on all the latest Karnataka news with The New Indian Express App. Download now
(Get the news that matters from New Indian Express on WhatsApp. Click this link and hit 'Click to Subscribe'. Follow the instructions after that.)

Comments

Disclaimer : We respect your thoughts and views! But we need to be judicious while moderating your comments. All the comments will be moderated by the newindianexpress.com editorial. Abstain from posting comments that are obscene, defamatory or inflammatory, and do not indulge in personal attacks. Try to avoid outside hyperlinks inside the comment. Help us delete comments that do not follow these guidelines.

The views expressed in comments published on newindianexpress.com are those of the comment writers alone. They do not represent the views or opinions of newindianexpress.com or its staff, nor do they represent the views or opinions of The New Indian Express Group, or any entity of, or affiliated with, The New Indian Express Group. newindianexpress.com reserves the right to take any or all comments down at any time.

flipboard facebook twitter whatsapp