Coach Lionel Scaloni included most of the players who won the Copa America in July, Argentina's first major title in almost 30 years.
Moments after the referee blew for full-time in the Copa America final between Argentina and Brazil, Lionel Messi was on his knees.
Di Maria, captain Lionel Messi and striker Sergio Agüero are the sole survivors of the squad that lost the 2014 World Cup final in Brazil.
Messi scored from a late freekick and earlier laid on two assists as Argentina eventually subdued Ecuador and kept the superstar's dream of winning his first major international title alive.
The 34-year-old Messi's 148th appearance for Argentina beat the mark previously held by retired defender Javier Mascherano.
Messi leads all Copa America scorers with three in four matches.
Argentina legend Diego Maradona died of a heart attack at the age of 60, weeks after undergoing brain surgery for a blood clot.
The win placed Lionel Messi's La Albiceleste top of Group A with seven points -- enough to secure its spot in the next phase of the tournament being played in empty stadiums.
The two sides seem unsure about which players to select for the Group A game at the Mane Garrincha stadium in Brasilia.
Captain Casemiro is yet to find out whether he will play as defensive midfielder next to Douglas Luiz, Fred or Lucas Paqueta.
Defender Juan Foyth and striker Lucas Ocampos are the most notable absentees from the 28-player squad, despite featuring regularly since Lionel Scaloni became head coach in 2018.
Chile lost midfielder Arturo Vidal to COVID-19 only two days before the clash against its rival. The same reason forced Lasarte to leave defender Paulo Díaz out.
Argentina will face traditional rivals Brazil, also in Saudi Arabia next Tuesday.
Argentina captain Lionel Messi only scored once in Russia and is still yet to net in the knockout stages of a World Cup.
A look at Colombia's matches at this World Cup and the 2014 edition in Brazil reveals they have been more effective in total than their bigger South American opponents while also playing fewer games.