Robert Lewandowski was shown his first red card in nearly a decade and Gerard Piqué was sent off from the bench in his last career match.
The 35-year-old defender cut his contract short, with a year-and-a-half yet to run, announcing his impending retirement on Thursday.
Prosecutors say Shakira moved to Spain in 2011 when her relationship with FC Barcelona defender Gerard Pique became public but maintained official tax residency in the Bahamas until 2015.
Spanish football hero Pique, 35, won the 2010 World Cup and the 2012 European Championship, and is a three-time Champions League winner with Barcelona.
Lopetegui never lost in 20 games as Spain boss, but even in a flawless qualifying campaign on the field, the Madrid-Barca rivalry.
Centre-back Pique took a knock to the knee at the team's World Cup headquarters in Krasnodar in a 50-50 challenge with striker Diego Costa.
The draw in front of a sold-out 50,653 crowd preserves both sides' respective unbeaten runs dating back to Euro 2016.
Spain coach Julen Lopetegui sought Sunday to downplay the potential impact of the Catalan independence bid on his team.
Spain comfortably defeated Albania 3-0 in a match in which defender Gerard Pique received a mixed reaction from the home supporters.
Pique has been mocked for posting he stays with a picture of him and Neymar together on Barca's pre-season tour to the US.
Gerard Pique delivered Barcelona's match winner over Real Madrid on Saturday as El Clasico Miami lived up to the hype.
Neymar has scored three goals in two friendlies for Barcelona but has studiously avoided speaking to the press.
Barcelona defender Pique remains convinced that Neymar will stay at Camp Nou, but said his opinion was based on intuition.
Neymar will stay with Barcelona, according to teammate Gerard Pique, who posted a Twitter message on the striker's status.