According to health officials, 12 boxes of the consignment are allotted for Ernakulam district and nine boxes will be sent to Kozhikode.
At least 1,300 people registered for vaccination are expected to get the first dose on the launch day. All centres had a thermal screening at the entrance.
The Centre has asked four states recording a surge in COVID-19 cases -- Maharashtra, Kerala, Chhattisgarh and Bengal -- to maintain a strict vigil.
The affected included two family members each from Kozhikode and Alappuzha, one each from Kottayam and Kannur.
Kerala has reported the maximum number of single-day recoveries with 5,707 newly recovered cases, 4,913 people recovered in Maharashtra followed by 1,588 in Chhattisgarh.
Research being conducted in Kozhikode has shown that mutation of the virus has been happening in the state also, said Kerala Health Minister KK Shailaja
Chennithala who does not have any symptoms will be shifted to the hospital.
The state on the day recorded 6,293 fresh cases and 4,749 recovered cases.
According to health officials, the sources of infection of 167 people could not be traced.
Of the new cases, 291 were contact transmission cases and four were health workers.
The dire prognosis comes at a time when the state is heading for the Christmas and New Year celebrations.
The newly-infected also include 5 healthcare workers and 6 migrant labourers. According to health officials, the sources of infection of 137 people could not be traced.
While the state-level steering committee is chaired by the chief secretary, the state task force is headed by the health principal secretary.
Meanwhile, 23 deaths in the last few days were confirmed on Friday as due to COVID-19 taking the death toll in the state to 2,757.
Pinarayi Vijayan said the quantity of the vaccine that would be allotted to the state by the Centre was not yet known.