Marseille should have taken the lead in the first half, but Arkadiusz Milik failed to convert two big chances for the hosts.
Marseille visit Feyenoord on April 28 in the first leg of their semi-final tie and then host the Dutch club in the return clash a week later.
Marseille trailed runaway leader Paris Saint-Germain by 12 points but kept a three-point cushion over third-place Rennes.
Simeone has worked wonders with Atletico Madrid since being appointed in late 2011 and winning the Europa League just six months later.
Koke could play off the front two of Griezmann and Diego Costa, offering the same kind of threat that saw him score the winner at Getafe in La Liga at the weekend.
Five minutes after coming on as a substitute, Rolando volleyed in a corner from captain Dimitri Payet in the 116th minute.
Patrice Evra's ban only applies to UEFA club competitions, meaning that he could still play in a domestic league.
Evra had been widely condemned for the assault on a Marseille fan which took place ahead of a Europa League tie at Vitoria Guimaraes.
Evra was widely condemned for the assault on a Marseille spectator which took place during the pre-match warm-up of a Europa League.
France coach Didier Deschamps predicted Patrice Evra would pay a heavy price for kicking a Marseille fan last week and says the former national captain should have known better.
Marseille fans have told Patrice Evra he is no longer welcome at the club after the defender kicked a supporter in the head.
A Marseille clothing designer is hoping to make hay with a hastily-designed t-shirt mocking Patrice Evra's karate kick on one of his team's own fans.
The French club's announcement came after UEFA said earlier Friday that Evra will be banned for at least one game.
Neymar was not only harried and niggled by a series of fouls in the game, but also pelted by Stade Velodrome fans with coins.
Neymar was both hero and villain as the Brazilian scored and was then sent off as PSG snatched a draw against Marseille.
PSG will unleash star strike duo Neymar and Kylian Mbappe on bitter foes Marseille for the first time this weekend.
Giroud has the right profile, but Garcia admits that the French international may have other interests than Marseille.