Ronaldo is currently self-isolating after testing positive for Covid-19 and will need to pass a negative test before being allowed to feature against Barcelona.
Lionel Messi hit the upright in the 20th minute and Antoine Griezmann wasted a great chance on the half-hour mark.
Barca host Hungarian side Ferencvaros on Tuesday and then face sworn enemies Real Madrid four days later behind closed doors at the Camp Nou.
Neymar's looming presence in the box brought a first penalty, which the star striker calmly converted to equalize in the 28th.
The hosts predictably dominated possession but struggled to break down an organized and physical Ecuador outfit that proved a different proposition to the one dispatched 6-1 in a friendly a year ago.
Messi pushed for a move away from the club this offseason only to change his mind after the club refused to let him leave for free, opting to stay instead of launching a potentially ugly battle.
If Messi leads Argentina to its third world title and first since 1986, it would finally win him a place in the hearts of Diego Maradona’s faithful.
The 33-year-old, a record six-time winner of the Ballon d'Or, has won everything in the club game with Barcelona several times over but his international trophy cabinet looks bare in comparison.
Paris Saint-Germain will have a chance for revenge against Manchester United, who ousted the French club in the last 16 two seasons ago.
In only his second interview since unsuccessfully pushing for a transfer in the offseason, Messi said Barcelona will be stronger if everyone works together to help the club succeed.
Suarez, who is Barcelona's third-highest scorer, joined Atletico Madrid on Thursday.
After marking Messi and Ronaldo in La Liga, Vicente Gomez ready for ISL challenge with Kerala Blasters
Vicente Gomez is a midfield dynamite who could break up the opposition's play and build attacks from the back.
Barcelona's Lionel Messi on Monday posted a farewell message for teammate Arturo Vidal, who is set to join Italian club Inter Milan.
Messi decided to stay at Barcelona to avoid a legal dispute with the club after having previously announced he wanted to leave to 'seek a new direction' in his career.
For long, Messi's bond with Barcelona was nothing short of mythical. The Messiah came, transformed and conquered...