Poland, which is in last place in the group with one point, could be without defender Jan Bednarek and midfielder Jakub Moder because of injury.
A loss would have ended Poland’s chances of reaching the round of 16 at Euro 2020.
The Bayern Munich striker was kept quiet by a Slovakia defence led by Milan Skriniar, the Inter Milan centre-back who scored the winning goal in Saint Petersburg.
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The future pillar of the national team got his start at this small schoolboy club that at the time only had rudimentary facilities, with dirt and sand instead of a proper pitch.
The 32-year-old Lewandowski is already the country’s leading scorer with 66 goals in a record 118 appearances
Lewandowski converted an early penalty in Bayern’s 2-2 draw at Freiburg and Poland forward matched Gerd Müller’s record from 1972. Bayern secured the title last weekend.
As part of his penalty celebrations, the Poland striker lifted his match shirt to reveal a picture of Gerd Mueller over the text "4ever Gerd".
Poland captain Lewandowski scored twice in a 3-0 win over Andorra on Sunday but was substituted in the 63rd minute with clear discomfort in his right knee.
With 28 goals in 22 league games, Lewandowski is on his way to being crowned the Bundesliga's top-scorer for the fourth season running.
Lewandowski scored his 22nd goal of the season – a league record after 17 games – from the spot after a foul from Augsburg midfielder Rani Khedira on Lucas Hernández.
Bayern Munich maintained the lead through to the first half but Freiburg's Nils Petersen levelled the scores after the hour mark.
Liverpool manager Jurgen Klopp won the Best Men's Coach award while Netherlands women's national-team boss Sarina Wiegman won the Best Women's Coach award
Lewandowski has taken 332 games to go past the 250-goal mark, while Fischer took 460 matches and Muller 284.
For Men's Goalkeeper of the Year, Alisson Becker from Liverpool and Manuel Neuer from Bayern Munich are among the shortlisted players.