KGH CoC lab boosts tribal blood disorder screening

It functions as a regional diagnostic centre for North Coastal Andhra
King George Hospital (KGH), Vizag
King George Hospital (KGH), VizagPhoto / Express
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VIJAYAWADA: Healthcare services for tribal communities in North Andhra have received a significant boost with the Centre of Competence (CoC) laboratory at King George Hospital (KGH), Vizag, facilitating early diagnosis and treatment of genetic blood disorders such as sickle cell disease and thalassemia.

Established for the first time in the State and launched in May this year, the laboratory is functioning as a regional diagnostic centre for Vizag, Vizianagaram, Srikakulam and ASR districts. The initiative is being implemented with special focus from State Health Minister Y Satya Kumar Yadav to provide advanced healthcare services to people in tribal areas.

The laboratory has tested 121 blood samples so far, with genetic haemoglobin variants or carrier conditions detected in 94 samples. It means that 77.7% of the samples tested showed genetic haemoglobin abnormalities or carrier status.

Among those diagnosed, 33 had sickle cell trait (HbAS), while 23 had homozygous sickle cell disease (HbSS). Thalassemia trait was detected in 10 people, thalassemia major in six and a combined sickle cell-thalassemia in other six. Rare variants such as HbD, HbC and HbE were in two people.

The CoC laboratory is equipped with advanced diagnostic techniques, including High-Performance Liquid Chromatography (HPLC), capillary electrophoresis and Variant Newborn Screening. So far, 70 samples have been tested through HPLC, 49 through capillary electrophoresis and two through Variant Newborn Screening.

Samples from KGH, government medical colleges, district and area hospitals, CHCs, PHCs and tribal health centres are tested at the laboratory. Samples collected under the National Sickle Cell Anaemia Elimination Mission also undergo testing. Those from remote tribal areas are transported in EDTA tubes and cold boxes maintained at 2-8 degrees Celsius.

Equipment and infrastructure worth Rs 2.85 crore have been provided for the CoC laboratory. Another Rs 16.93 lakh has been allocated annually under Annual Maintenance Contracts for equipment upkeep, while Rs 45.54 lakh has been deposited into the KGH CFMS account for reagents and testing kits.

KGH Superintendent E Vani said diagnostic tests, genetic counselling and clinical management services were being provided free of cost.

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