STOCK MARKET BSE NSE

Oxford COVID-19 vaccine may become the first to get regulator's nod in India: Sources

The Pune-based SII, the world's largest vaccine manufacturer, has made a collaboration with the University of Oxford and AstraZeneca.

Published: 26th December 2020 10:25 PM  |   Last Updated: 26th December 2020 10:25 PM   |  A+A-

covid_vaccine

For representational purposes. (Photo | AP)

By PTI

NEW DELHI: With preparations underway for a possible vaccine-rollout by January, the Indian drug regulator is looking at the UK, which sources believe may give its nod to the Oxford COVID-19 vaccine next week, before deciding on giving emergency use authorisation to the Serum Institute that is manufacturing the shots here.

Once the UK drug regulator gives its approval to the Oxford vaccine, the expert committee on COVID-19 at the CDSCO will hold its meeting and thoroughly review the safety and immunogenicity data from the clinical evaluations conducted abroad and in India before granting any emergency authorisation for the vaccine here, official sources said.

The process of granting emergency use approval for Bharat Biotech's COVID-19 vaccine 'Covaxin' may take time as its phase 3 trials are still underway, while Pfizer is yet to make a presentation.

"Going by this, Oxford vaccine 'Covishield' is likely to be the first to be rolled out in India,"  a source said.

Serum Institute of India (SII) last week also had submitted some additional data required by the Drug Controller General of India (DCGI), the sources said.

Amid fears about the mutated variant of SARS-CoV-2 detected in the UK, government officials recently said that it will have no impact on the potential of emerging vaccines that are being developed in India and other countries.

Bharat Biotech, Serum Institute of India (SII) and Pfizer had applied to the Drugs Controller General of India  (DCGI) seeking emergency use authorisation for their COVID-19 vaccines early this month.

The subject expert committee (SEC) on COVID-19 of the Central Drugs Standard Control Organisation (CDSCO) on December 9 had sought additional safety and efficacy data for COVID-19 vaccines of SII and Bharat Biotech after deliberating upon their applications.

The application by the Indian arm of US pharmaceutical firm Pfizer was not taken up for deliberation as the company had sought more time for making a presentation before the committee.

The Pfizer vaccine has already been approved by several countries including the UK, the US, and Bahrain.

While considering SII's application, the SEC had recommended that the firm should submit an updated safety data of phase 2 and 3 clinical trials in the country, immunogenicity data from the clinical trial in the UK and India, along with the outcome of the assessment of the UK Medicines and Healthcare products Regulatory Agency (MHRA) for grant of EUA.

As for Hyderabad-based Bharat Biotech, "after detailed deliberation, the committee recommended that the firm should present the safety and efficacy data from the ongoing phase 3 clinical trial in the country for further consideration", the SEC had said.

The Pune-based SII, the world's largest vaccine manufacturer, has made a collaboration with the University of Oxford and AstraZeneca to manufacture the vaccine.

The SII has already manufactured 40 million doses of the vaccine, under the at-risk manufacturing and stockpiling licence from the DCGI, officials recently had said.



Comments(1)

Disclaimer : We respect your thoughts and views! But we need to be judicious while moderating your comments. All the comments will be moderated by the newindianexpress.com editorial. Abstain from posting comments that are obscene, defamatory or inflammatory, and do not indulge in personal attacks. Try to avoid outside hyperlinks inside the comment. Help us delete comments that do not follow these guidelines.

The views expressed in comments published on newindianexpress.com are those of the comment writers alone. They do not represent the views or opinions of newindianexpress.com or its staff, nor do they represent the views or opinions of The New Indian Express Group, or any entity of, or affiliated with, The New Indian Express Group. newindianexpress.com reserves the right to take any or all comments down at any time.

  • SHARATH AHUJA

    As a lay person, my only question here is: Is there any liability on the Companies that make the vaccines to guarantee their efficacy. Or will there be in fine print (not readable or understandable any way) that we absolve ourselves of any side effects?
    3 months ago reply
flipboard facebook twitter whatsapp