Coach Lopetegui successfully blended emerging talent with the experience provided by veterans to qualify for an 11th straight World Cup.
Andres Iniesta became the latest big-name player to join the J-League after agreeing terms with Vissel Kobe on Thursday.
Andres Iniesta, who lifted 32 major trophies and made 674 appearances for Catalan giants Barca was unveiled by Vissel.
Andres Iniesta bows out with Barcelona win thanks to brilliant Philippe Coutinho strike against Real Sociedad
Iniesta, with a tear in his eye, walked off to a standing ovation from the Camp Nou when substituted in the second half, having unfastened his captain's armband and handed it to Lionel Messi.
The draw in front of a sold-out 50,653 crowd preserves both sides' respective unbeaten runs dating back to Euro 2016.
The Spanish federation said Iniesta and Morata have muscle injuries and Carvajal has a viral infection related to his heart.