After a goalless first half came to an end, Leicester City took the lead 10 minutes into the second half, thanks to Maddison's well-executed goal.
The 32-year-old has been a mainstay in City's defence since his arrival at King Power Stadium and has featured on 89 occasions in all competitions to-date, scoring three goals.
Rashford had appeared to damage his shoulder towards the end of the match against Leicester but Solskjaer is hopeful that it is not a serious concern.
Bruno Fernandes looked to be sending United to its seventh straight away win when he scored in the 79th minute, moving onto 10 goals in his first full season in the league.
Defensive midfielder McTominay — who hadn't scored in the EPL since March — netted in the second and third minutes after he was left plenty of space.
Tottenham's title aspirations will be put to the test with City, Chelsea, Arsenal, Liverpool and Leicester to come in their next six games.
With this victory against Wolves, Leicester City have claimed the top spot on the Premier League table with 18 points.
Leicester City star James Justin praised the team's performance and said that his side has shown this season that they react well to adversity.
A minute of silence was held ahead of the game between Nice and Hapoel Beer Sheva to honor the three victims of a knife attack in the French city.
Arsenal are languishing in 10th after a second consecutive league loss following their 1-0 defeat at Manchester City last weekend.
Aston Villa claimed a fourth straight win to open the EPL season as Ross Barkley scored in stoppage time to secure a 1-0 victory over Leicester City.
Darnell Johnson has joined League One side Wigan Athletic on loan until January 2021, subject to Football League approval.
It was a concerning display by Pep Guardiola’s side, which was without a slew of key players through injury and issues related to COVID-19.
Ndidi was not involved in Leicester's 2-0 loss to Arsenal in the English League Cup after getting hurt in the 4-2 win over BurnleNdidi was not involved in Leicester's 2-0 loss to Arsenal in the English League Cup after getting hurt in the 4-2 win over Burnley in the Premier League on Saturday.y in the Premier League on Saturday.
Castagne, a defensive signing from Atalanta, made an impact at the other end by heading in a cross from fellow Belgian Dennis Praet in the 56th minute.