According to the NHK broadcaster, the chicken farm, located in the town of Shirosato, started slaughtering about 840,000 chickens on Tuesday morning.
Zoo Director Ramesh Pandey said they were following all protocols and monitoring the situation strictly.
People have been requested to be vigilant and consume chicken meat, eggs and other poultry products only after proper cooking.
Advisories have already been issued to the authorities concerned for strengthening the active and targeted surveillance against the disease.
No bird flu case in Karnataka, officials asked to remain on alert: Animal Husbandry Minister Prabhu Chauhan
Transportation of poultry and its products from Kerala into the state had been completely prohibited, Prabhu Chauhan said.
Over four lakh poultry birds died at some farms in Haryana's Panchkula district over the past several days.
The Punjab government banned the import of poultry birds from other states with immediate effect till January 15.
States have been told to ensure sufficient stock of PPE kits and accessories required for culling operations.
A three-member central team on Thursday took stock of the situation arising out of outbreak of bird flu in Alappuzha.