On the other hand, Bharti Airtel slipped 1.98 per cent, Kotak Bank 1.38 per cent, Bajaj Auto 0.88 per cent, Asian Paints 0.31 per cent, HDFC Bank 0.05 per cent and HUL 0.03 per cent.
Tata Motors was the top gainer in the Sensex pack rallying up to 3.78 per cent, followed by Vedanta, Yes Bank, Tata Steel, SBI, M&M, Axis Bank and RIL.
On the other hand, Infosys fell 2.63 per cent, ONGC 1.68 per cent, HCL Tech 1.51 per cent, TCS 1.20 per cent and Bharti Airtel 0.95 per cent.
According to traders domestic investors following cues from global markets, which were enthused by US Federal Reserve's dovish outlook in its policy meet last night.
In Sensex, ICICI Bank emerged as the biggest gainer with 0.88 per cent rise, followed by Mahindra & Mahindra, ITC, Bajaj Finance, TCS, Tata Steel, NTPC, L&T and HDFC.
It finally closed 247.55 points or 0.61 per cent lower at 40,239.88. On similar lines, the 50-scrip NSE Nifty fell 80.70 points or 0.68 per cent to finish at 11,856.80.
Top losers in the Sensex pack in early trade included Yes Bank, TCS, Tech Mahindra, PowerGrid, Infosys, Axis Bank, ITC and IndusInd Bank, falling up to 2.22 per cent.
Among the Sensex stocks, HDFC emerged as the top gainer, rising by 2.06 per cent, followed by Axis Bank, Maruti, Reliance, Power Grid and Tata Steel.
Power metres intact, fire might have started in internal system of building: BSES on Delhi fire mishap
Thirty fire tenders rushed to the spot after the fire department received information about the incident.
The index finally settled at 40,445.15, down 334.44 points or 0.82 per cent. Likewise, the 50-share Nifty shed 96.90 points or 0.81 per cent to settle at 11,921.50.
The BSE gauge Sensex moved 103.13 points higher to trade at 40,882.72 in opening deals; while the NSE barometer Nifty added 22.50 points to 12,040.90.
On the Sensex chart, Bharti Airtel, Tata Steel, IndusInd Bank, HeroMoto Corp and Tata Motors were among the major laggards.
The Sensex gains were driven by heavyweight Reliance Industries, followed by automakers like Heromoto Corp and Tata Motors.
Exchange data showed foreign institutional investors (FIIs) sold equities worth Rs 1,131.12 crore on Tuesday.
The performance of the candidates who answer the wrong combination of question papers will be cancelled.