Congress leader Sanjay also questioned the recent meet of the NCP chief Sharad Pawar with Prime Minister Narendra Modi in Delhi.
To emphasise his point, Nirupam drew parallels with Congress forging an alliance with BSP in Uttar Pradesh years ago, pointing out that the party has not been able to revive after that.
Congress has moved its MLAs to a resort in Jaipur in Rajasthan, a Congress-ruled state, while NCP has called its meet on November 12.
Former Congress CMs Ashok Chavan and Prithviraj Chavan have spoken about the need for the Shiv Sena to break away from the BJP in case it wants to form government with their party's support.
Both Deora and Nirupam, former presidents of Mumbai Congress, had stayed away from Gandhi's rallies in Mumbai on Sunday.
Both the leaders have worked at preeminent positions in the party and need to introspect that if their actions are helping those that have harmed the nation, he asserted.
Congress spokesperson Manish Tewari also asked former Haryana Congress chief Ashok Tanwar to stop making statements against the party ahead of assembly polls.
The Congress won 52 seats in the recent general elections, which is just eight more than what the party won in 2014 polls.
Infighting in Congress’ Haryana unit reaches Sonia Gandhi’s doorstep as Ashok Tanwar protests in Delhi; Sanjay Nirupam says he will stay away from Maharashtra election.
The former MP also said that considering the leadership's attitude towards him, he might quit the party soon.
While Deora did not name anyone, Nirupam had won from Mumbai North Lok Sabha seat in 2009, losing to BJP's Gopal Shetty by a massive margin in 2014.
'Confidential letter' to Milind Deora written before elections, leak was 'unfortunate': Urmila Matondkar
The Congress leader had criticised the conduct of Sandesh Kondvilkar and Bhushan Patil, close associates of Nirupam, in her letter that went viral.
In the missive, she highlighted the failure of party leadership at local level on coordination, mobilising workers at grassroots, failure to provide proper resources to her by the two coordinators.
Nirupam also criticised Deora's suggestion to set up a panel comprising three senior Congress leaders to oversee the Mumbai unit till the state Assembly polls, saying such a move would ruin the party.
In one case, the Delhi High Court had quashed the summons issued against Irani in a defamation complaint filed against her by Nirupam.