The rescued children are all minors and were being taken to work as bonded labourers in Surat district of Gujarat.
The couple are facing death penalty charges for drug trafficking, although sentences are rarely carried out.
The three used to run the brothel by procuring and trafficking girls, both minor and major.
Acting on a tip-off, a police team rescued 17 girls from a bus at Jeypore bus stand and nabbed the 26-year-old man who was accompanying them.
The prosecutors said the women had very little education and were asked to sign employment contracts which obliged them to pay an exorbitant financial penalty if they chose to terminate the contract.
Among the 384 human trafficking victims who were rescued from the State, 241 were trafficked for 'sexual exploitation for prostitution'.
Luring them with job offers in five star hotels, nine such victims were being taken to Maldives as bonded labourers
The trial could be the most costly since litigation against tobacco companies in the 1990s, which showed cigarette companies cynically hiding and exploiting the dangers of tobacco for profits.
All of the children, aged 10 to 13, were trafficked into the Indian Territory from the interiors of Nepal, which shares a border with India at Sitamarhi district of Bihar.
Investigation revealed that the parcel, bound for Malaysia, was despatched by a firm named J V Export.
The arrested used to target minor girls who fled from their houses and are picked up from railway stations.
US and Chinese officials will now have 'routine conversations' and the Americans will share more specific case data to help their counterparts in China 'better target' drug traffickers.
Mohammed Tahir Ayaz, 26, and his wife Ikra Hussain, 20, of Huddersfield, West Yorkshire, could face the death penalty for attempting to smuggle heroin to the UK via Dubai.
The boys, who were worried about cracking entrance tests were brought from Kota to B’luru
The women were rescued by the police with the support of Maiti Nepal, a NGO which has earlier worked to rescue Nepalese girl.