Former Delhi CM Arvind Kejriwal and his deputy Manish Sisodia were cleared of all charges in the Delhi excise policy case.
The trial court also discharged 21 others, citing lack of evidence and gaps in the CBI chargesheet.
Telangana Jagruthi president K Kavitha was also acquitted.
The CBI has said it will appeal in the Delhi High Court. Kejriwal called the case the biggest political conspiracy in independent India.